Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483227 | 0.94 | MET (0.50) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL29773372 | 0.94 | MET (0.50) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2177639 | 0.91 | MET (0.54) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12690022 | 0.88 | MET (0.52) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2177521 | 0.86 | MET (0.50) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12489841 | 0.85 | MET (0.68) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL29773404 | 0.85 | MET (0.68) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2570437 | 0.79 | MET (0.68) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12489713 | 0.78 | MET (0.67) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2175503 | 0.78 | MET (0.68) | METCYP2C9PDE3BPDE3APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519524-A1 | CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | Hutchison Medipharma Limited (CN) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011079804-A1 | CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-07-07 | — | — | WO | disclosed |