SCHEMBL21780112

SCHEMBL21780112

NC/C(=C/F)COc1ccc(C(=O)N2CCC(c3ccccc3)CC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC2 O75106 13/20 0.57
HSD11B1 P28845 1/20 0.54
MAOA P21397 5/20 0.53
MAOB P27338 3/20 0.53
DAO P14920 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ALDH1A1 P00352 2/20 0.51
GAA P10253 2/20 0.51
MAPT P10636 2/20 0.51
RAB9A P51151 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21780111 1.00 AOC2 (0.57) AOC2HSD11B1MAOAMAOBDAO
Trifluoroacetic Acid SCHEMBL21768058 0.95 AOC2 (0.53) AOC2HSD11B1MAOAMAOBDAO
Trifluoroacetic Acid SCHEMBL21768086 0.95 AOC2 (0.53) AOC2HSD11B1MAOAMAOBDAO
Trifluoroacetic Acid SCHEMBL21768088 0.95 AOC2 (0.53) AOC2HSD11B1MAOAMAOBDAO
Trifluoroacetic Acid SCHEMBL21768163 0.81 PARP14 (0.43) AOC2HSD11B1CA12CA1CA2
Trifluoroacetic Acid SCHEMBL21768095 0.81 PARP14 (0.43) AOC2HSD11B1CA12CA1CA2
Trifluoroacetic Acid SCHEMBL30089533 0.81 PARP14 (0.43) AOC2HSD11B1CA12CA1CA2
Trifluoroacetic Acid SCHEMBL21768120 0.81 PARP14 (0.43) AOC2HSD11B1CA12CA1CA2
Trifluoroacetic Acid SCHEMBL30089559 0.81 PARP14 (0.43) AOC2HSD11B1CA12CA1CA2
SCHEMBL21780142 0.78 AOC2 (0.56) AOC2MAOAMAOBDAOCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617186-A1 FLUOROALLYLAMINE DERIVATIVE AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-03-04 EP disclosed