Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14480767 | 0.88 | HRH3 (0.37) | HTR2AHTR2CHTR2BAXLHRH3 | |
| SCHEMBL14480898 | 0.88 | HRH3 (0.37) | HTR2AHTR2CHTR2BAXLHRH3 | |
| SCHEMBL21780459 | 0.88 | HRH3 (0.37) | HTR2AHTR2CHTR2BAXLHRH3 | |
| SCHEMBL21780490 | 0.85 | HRH3 (0.37) | HTR2AHTR2CHTR2BAXLHRH3 | |
| SCHEMBL14480765 | 0.85 | HRH3 (0.37) | HTR2AHTR2CHTR2BAXLHRH3 | |
| SCHEMBL14480503 | 0.85 | HRH3 (0.37) | HTR2AHTR2CHTR2BAXLHRH3 | |
| SCHEMBL15105998 | 0.85 | MCHR1 (0.38) | HTR2AHTR2CHTR2BAXLKCNH2 | |
| SCHEMBL21780397 | 0.84 | AR (0.43) | HTR2AHTR2CHTR2BHRH3MEN1 | |
| SCHEMBL14480619 | 0.84 | AR (0.43) | HTR2AHTR2CHTR2BHRH3MEN1 | |
| SCHEMBL14481095 | 0.84 | AR (0.43) | HTR2AHTR2CHTR2BHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101013-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |