Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23426235 | 1.00 | FFAR4 (0.35) | FFAR4LMNAGAAALDH1A1CYP2D6 | |
| SCHEMBL22650291 | 0.84 | LMNA (0.38) | LMNAGAAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL21780664 | 0.83 | LMNA (0.37) | LMNAGAAALDH1A1KDM4ESLC6A2 | |
| SCHEMBL21780658 | 0.76 | LMNA (0.39) | LMNAGAAALDH1A1CYP2C19KDM4E | |
| SCHEMBL21780611 | 0.72 | APP (0.33) | FFAR4CHRM4CHRM1 | |
| SCHEMBL31072028 | 0.71 | FFAR4 (0.32) | FFAR4CHRM4CHRM1 | |
| SCHEMBL21767615 | 0.71 | FFAR4 (0.32) | FFAR4CHRM4CHRM1 | |
| SCHEMBL21767379 | 0.69 | BACE1 (0.31) | — | |
| SCHEMBL31072020 | 0.69 | BACE1 (0.31) | — | |
| SCHEMBL15063187 | 0.68 | GAA (0.50) | LMNAGAAALDH1A1KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617206-A1 | INTEGRIN INHIBITORS | Morphic Therapeutic, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |