Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 16/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 16/20 | 0.50 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780749 | 0.94 | MAOA (0.54) | MAOAMAOBESR1ESR2MIF | |
| SCHEMBL6208215 | 0.89 | ESR2 (0.58) | MAOAMAOBESR1ESR2MIF | |
| SCHEMBL21780904 | 0.86 | MAOA (0.47) | MAOAMAOBESR1ESR2MIF | |
| SCHEMBL21780918 | 0.85 | MAOA (0.46) | MAOAMAOBESR1ESR2 | |
| SCHEMBL16847161 | 0.79 | ESR1 (0.50) | MAOAMAOBESR1ESR2MIF | |
| SCHEMBL21780770 | 0.76 | ESR1 (0.55) | MAOAMAOBESR1ESR2 | |
| SCHEMBL30251430 | 0.75 | MAOB (1.00) | MAOAMAOBESR2 | |
| SCHEMBL1091999 | 0.75 | MAOB (1.00) | MAOAMAOBESR2 | |
| SCHEMBL26777072 | 0.75 | MAOA (0.64) | MAOAMAOBESR1ESR2MIF | |
| Water SCHEMBL15676351 | 0.74 | MAOB (0.96) | MAOAMAOBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233828-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-03-04 | — | — | EP | disclosed |