Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.72 |
| ▸ | TUBB | P07437 | 2/20 | 0.72 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.72 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.72 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.72 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.72 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.72 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.72 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.72 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.72 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.72 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.72 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.72 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.72 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 13/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15953834 | 0.88 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28453223 | 0.88 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18327915 | 0.88 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16346487 | 0.88 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19904032 | 0.87 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20442788 | 0.86 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8380699 | 0.84 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7499142 | 0.84 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18473277 | 0.83 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17155697 | 0.82 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233828-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-03-04 | — | — | EP | disclosed |