Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 10/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894301 | 0.92 | PTGER1 (0.65) | PTGER1THRBCA12CA1CA2 | |
| SCHEMBL2176713 | 0.91 | PTGER1 (0.61) | PTGER1THRBCA12CA1CA2 | |
| SCHEMBL12407575 | 0.88 | PTGER1 (0.57) | PTGER1THRBCA12CA1CA2 | |
| SCHEMBL27770490 | 0.88 | PTGER1 (0.51) | PTGER1THRBCA12CA1CA2 | |
| SCHEMBL2175495 | 0.86 | PTGER1 (0.63) | PTGER1THRBKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL2175531 | 0.86 | PTGER1 (0.55) | PTGER1THRBCA12CA1CA2 | |
| SCHEMBL2176680 | 0.86 | PTGER1 (0.65) | PTGER1THRBALDH1A1LMNAHPGD | |
| SCHEMBL12407580 | 0.85 | PTGER1 (0.53) | PTGER1THRBCA12CA1CA2 | |
| SCHEMBL12482052 | 0.84 | PTGER1 (0.66) | PTGER1THRBCNR2 | |
| SCHEMBL2176553 | 0.83 | PTGER1 (0.61) | PTGER1THRBALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973078-B2 | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-05 | — | — | US | claimed |