Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 13/20 | 0.48 |
| ▸ | CA1 | P00915 | 13/20 | 0.48 |
| ▸ | CA2 | P00918 | 13/20 | 0.48 |
| ▸ | CA4 | P22748 | 13/20 | 0.48 |
| ▸ | CA9 | Q16790 | 13/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178144 | 0.88 | PTGER1 (0.63) | PTGER1CA12CA1CA2CA4 | |
| SCHEMBL27749427 | 0.85 | PTGER1 (0.50) | PTGER1THRB | |
| SCHEMBL27749658 | 0.85 | PTGER1 (0.51) | PTGER1CA1CA2THRB | |
| SCHEMBL12407575 | 0.85 | PTGER1 (0.57) | PTGER1CA12CA1CA2CA4 | |
| SCHEMBL2176713 | 0.85 | PTGER1 (0.61) | PTGER1CA12CA1CA2CA4 | |
| SCHEMBL2175531 | 0.85 | PTGER1 (0.55) | PTGER1CA12CA1CA2CA4 | |
| SCHEMBL12407580 | 0.83 | PTGER1 (0.53) | PTGER1CA12CA1CA2CA4 | |
| SCHEMBL27749426 | 0.82 | THRB (0.52) | PTGER1THRB | |
| SCHEMBL12407581 | 0.81 | PTGER1 (0.51) | PTGER1CA12CA1CA2CA4 | |
| SCHEMBL12481532 | 0.81 | PTGER1 (0.51) | PTGER1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | claimed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | claimed |
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |