Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.34 |
| ▸ | FURIN | P09958 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068135 | 1.00 | MAP1LC3B (0.35) | MAP1LC3BKLKB1FURINMEN1KMT2A | |
| SCHEMBL22068484 | 0.95 | KLKB1 (0.34) | MAP1LC3BKLKB1FURINMEN1KMT2A | |
| SCHEMBL22068138 | 0.94 | KLKB1 (0.34) | MAP1LC3BKLKB1FURINTP53FAP | |
| SCHEMBL21781788 | 0.94 | FURIN (0.34) | MAP1LC3BKLKB1FURINMEN1KMT2A | |
| SCHEMBL22068550 | 0.91 | MAP1LC3B (0.37) | MAP1LC3BKLKB1FURINMEN1KMT2A | |
| SCHEMBL22068547 | 0.86 | MAP1LC3B (0.36) | MAP1LC3BKLKB1FURINTP53FAP | |
| SCHEMBL30988377 | 0.80 | FURIN (0.42) | FURINC3AR1 | |
| SCHEMBL30988360 | 0.80 | MAP1LC3B (0.35) | MAP1LC3BKLKB1FURINTP53FAP | |
| SCHEMBL30988380 | 0.80 | MAP1LC3B (0.35) | MAP1LC3BKLKB1FURINMEN1KMT2A | |
| SCHEMBL22068095 | 0.78 | MAP1LC3B (0.36) | MAP1LC3BKLKB1FURINMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |