Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782153 | 0.91 | OXER1 (0.66) | OXER1 | |
| SCHEMBL21781996 | 0.82 | OXER1 (0.77) | OXER1 | |
| SCHEMBL21782028 | 0.79 | OXER1 (0.69) | OXER1 | |
| SCHEMBL18126622 | 0.79 | OXER1 (0.85) | OXER1 | |
| SCHEMBL21782189 | 0.77 | OXER1 (0.78) | OXER1 | |
| SCHEMBL21782203 | 0.75 | OXER1 (0.68) | OXER1 | |
| SCHEMBL21781998 | 0.74 | OXER1 (0.60) | OXER1 | |
| SCHEMBL21782183 | 0.70 | OXER1 (0.84) | OXER1 | |
| SCHEMBL18126621 | 0.70 | OXER1 (1.00) | OXER1 | |
| SCHEMBL20014577 | 0.69 | OXER1 (0.74) | OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277665-B1 | INDOLE ANALOGS AS 5-OXO-ETE RECEPTOR ANTAGONISTS AND METHOD OF USE THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2020-03-04 | — | — | EP | disclosed |