Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22182585 | 0.82 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL256045 | 0.82 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL15871031 | 0.80 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10742280 | 0.80 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10742284 | 0.80 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18270126 | 0.77 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27616251 | 0.77 | — | — | |
| SCHEMBL16770286 | 0.76 | TRIM24 (0.60) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16770285 | 0.76 | TRIM24 (0.60) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10178210 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3617192-A1 | VIRAL REPLICATION INHIBITORS | Katholieke Universiteit Leuven K.U. Leuven R&D (BE) | 2020-03-04 | — | — | EP | disclosed |