Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.34 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ADA | P00813 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082493 | 0.77 | PRMT5 (0.37) | — | |
| SCHEMBL21082387 | 0.71 | CCNB2 (0.34) | ADORA2AADORA1ADORA2BALDH1A1ADA | |
| SCHEMBL21782407 | 0.71 | CCNB2 (0.42) | ADORA1ADORA3 | |
| SCHEMBL21082442 | 0.69 | — | — | |
| SCHEMBL21782435 | 0.67 | CDK1 (0.44) | ADORA2AADORA1ADORA2BADORA3PDE4D | |
| SCHEMBL21082443 | 0.65 | HPRT1 (0.42) | — | |
| SCHEMBL24435571 | 0.65 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BALDH1A1ADA | |
| SCHEMBL21082477 | 0.63 | — | — | |
| SCHEMBL20014135 | 0.63 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL22475026 | 0.63 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BALDH1A1ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682905-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3492109-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2020-03-04 | — | — | EP | disclosed |