Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CDC20 | Q12834 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782407 | 0.85 | CCNB2 (0.42) | CDK1ADORA3ADORA1CCNB1 | |
| SCHEMBL22224567 | 0.76 | CDK2 (0.44) | CDK1CDK2PRKACACCNA2PRKACG | |
| SCHEMBL21082387 | 0.75 | CCNB2 (0.34) | CDK1ADORA1ADORA2BCCNB1PDE4D | |
| SCHEMBL21082443 | 0.74 | HPRT1 (0.42) | — | |
| SCHEMBL21082477 | 0.73 | — | — | |
| SCHEMBL24829641 | 0.73 | CDK1 (0.53) | CDK1CDK2PRKACACCNA2PRKACG | |
| SCHEMBL21082621 | 0.72 | CCNB2 (0.41) | CDK1CDK2ADORA1CCNB1PDE4D | |
| SCHEMBL9582893 | 0.71 | CDK1 (0.45) | CDK1CDK2PRKACACCNA2PRKACG | |
| SCHEMBL19049976 | 0.71 | HSP90AB1 (0.42) | CDK1CDK2PRKACACCNA2PRKACG | |
| SCHEMBL24707517 | 0.70 | CDK2 (0.67) | CDK1CDK2PRKACACCNA2PRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682905-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3492109-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2020-03-04 | — | — | EP | disclosed |