Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.53 |
| ▸ | AHCY | P23526 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19049964 | 0.89 | CDK1 (0.52) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL19049976 | 0.88 | HSP90AB1 (0.42) | CDK1CDK2CCNB1CCNE1HSP90AA1 | |
| SCHEMBL25614254 | 0.86 | CDK1 (0.39) | CDK1CDK2CCNB1CCNE1 | |
| SCHEMBL21710849 | 0.82 | ADORA2A (0.49) | CDK1CDK2CCNB1CCNE1ADORA2A | |
| SCHEMBL23982304 | 0.81 | CDK1 (0.54) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL25605605 | 0.80 | CDK1 (0.50) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL23169714 | 0.79 | MEN1 (0.52) | — | |
| SCHEMBL24829634 | 0.79 | CCNE1 (0.55) | CDK1CDK2CCNB1CCNE1AHCY | |
| SCHEMBL22224567 | 0.75 | CDK2 (0.44) | CDK1CDK2CCNB1CCNE1PRKACA | |
| SCHEMBL24082030 | 0.75 | CDK2 (0.36) | CDK1CDK2CCNB1CCNE1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542505-B1 | Substituted RIG-I agonists: compositions and methods thereof | MERCK SHARP & DOHME LLC (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542505-B1 | Substituted RIG-I agonists: compositions and methods thereof | MAVS, TLR3, DDX18 | CDK1 4008/4885CDK2 3569/4885CCNB1 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.