SCHEMBL2178266

SCHEMBL2178266

c1ccc2[nH]c(-c3ccc(-c4nc5ccccc5[nH]4)cc3)nc2c1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 12/20 0.88
RAB9A P51151 12/20 0.88
GAA P10253 1/20 0.88
KDM4E B2RXH2 12/20 0.81
ALDH1A1 P00352 11/20 0.81
SMN1; SMN2 Q16637 10/20 0.81
HPGD P15428 6/20 0.81
HSD17B10 Q99714 4/20 0.81
MAPT P10636 4/20 0.81
TP53 P04637 3/20 0.81
POLB P06746 2/20 0.81
GFER P55789 1/20 0.81
PKM P14618 6/20 0.78
ABCB11 O95342 1/20 0.78
NPSR1 Q6W5P4 1/20 0.78
PKN1 Q16512 1/20 0.78
PKN2 Q16513 1/20 0.78
HDAC6 Q9UBN7 1/20 0.73
KMT2A Q03164 2/20 0.69
MMP2 P08253 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386825 1.00 NPC1 (0.88) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL24295036 0.98 NPC1 (0.84) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL22499602 0.96 NPC1 (0.81) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL2252555 0.94 NPC1 (0.92) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL105095 0.93 NPC1 (1.00) NPC1RAB9AGAAKDM4EALDH1A1
Benzene SCHEMBL28005151 0.93 NPC1 (1.00) NPC1RAB9AGAAKDM4EALDH1A1
Potassium SCHEMBL4891434 0.91 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL2147022 0.91 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL4775610 0.91 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL467859 0.91 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110713605-B Iron-containing metal-organic coordination polymer, preparation method and application 重庆文理学院 2022-02-15 CN claimed
US-20210075030-A1 BILAYER ELECTROLYTE MEMBRANE AND A REDOX FLOW BATTERY COMPRISING A BILAYER ELECTROLYTE MEMBRANE PAUL SCHERRER INSTITUT (CH) 2021-03-11 US claimed
US-10673007-B2 OLED device and method for manufacturing the same, OLED display panel and device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2020-06-02 US claimed
CN-107011525-B Zinc metal organic framework material and preparation method and application thereof 宁波大学 2020-03-31 CN claimed
US-10573830-B2 Flexible display panel and method of fabricating flexible display panel AU OPTRONICS CORP. (TW) 2020-02-25 US claimed
CN-110713605-A Iron-containing metal-organic coordination polymer, preparation method and application 重庆文理学院 2020-01-21 CN claimed
EP-3511999-A1 BILAYER ELECTROLYTE MEMBRANE AND A REDOX FLOW BATTERY COMPRISING A BILAYER ELECTROLYTE MEMBRANE PAUL SCHERRER INSTITUT (CH) 2019-07-17 EP claimed
US-20190131561-A1 OLED DEVICE AND METHOD FOR MANUFACTURING THE SAME, OLED DISPLAY PANEL AND DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2019-05-02 US claimed
US-20170294611-A1 FLEXIBLE DISPLAY PANEL AND METHOD OF FABRICATING FLEXIBLE DISPLAY PANEL AU OPTRONICS CORP. (TW) 2017-10-12 US claimed
US-9472772-B2 Display device AU OPTRONICS CORPORATION (TW) 2016-10-18 US claimed
US-6228922-B1 IMMERSING POLYMER IN SOLUTION CONTAINING METAL PRECURSOR, REDUCING TO METAL TO ENTRAP IN POLYMER THE UNIVERSITY OF DAYTON 2001-05-08 US claimed
US-5726282-A Light emitting diode RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-03-10 US claimed
EP-0374626-B1 Laminated polarisers BAYER AG (DE) 1995-03-01 EP claimed
US-5288529-A Lmination of two continuous biaxially oreinted films; useful for printed circuits boards FOSTER-MILLER INC. (US) 1994-02-22 US claimed
US-5223588-A In situ polymerization of rigid rod and matrix polymers GENCORP INC. (US) 1993-06-29 US claimed
EP-0477291-A4 LIQUID CRYSTAL POLYMER FILM 1992-11-19 EP claimed
EP-0477291-A1 LIQUID CRYSTAL POLYMER FILM FOSTER-MILLER ASSOCIATES, INC. (US) 1992-04-01 EP claimed
WO-1990015706-A1 LIQUID CRYSTAL POLYMER FILM FOSTER-MILLER, INC. (US) 1990-12-27 WO claimed
US-4842924-A HIGH COMPRESSIVE, TENSILE STRENGTH FARRIS RICHARD J (US) 1989-06-27 US claimed
US-4606875-A Process for preparing shaped articles of rigid rod heterocyclic liquid crystalline polymers CELANESE CORPORATION (US) 1986-08-19 US claimed