Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014349 | 0.95 | SIGMAR1 (0.30) | — | |
| SCHEMBL11010031 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL5183304 | 0.73 | EPHX1 (0.32) | — | |
| SCHEMBL331381 | 0.73 | EPHX1 (0.32) | — | |
| SCHEMBL11863846 | 0.73 | TSHR (0.34) | SCN1AKCNH2SCN2ASCN3A | |
| SCHEMBL19315953 | 0.73 | EPHX1 (0.32) | — | |
| SCHEMBL2573206 | 0.73 | CYP3A4 (0.34) | SCN1AKCNH2SCN2ASCN3A | |
| SCHEMBL2575329 | 0.73 | CYP3A4 (0.34) | SCN1AKCNH2SCN2ASCN3A | |
| SCHEMBL10836392 | 0.73 | CYP3A4 (0.34) | SCN1AKCNH2SCN2ASCN3A | |
| SCHEMBL737440 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519499-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080211-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |