Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | NNMT | P40261 | 1/20 | 0.58 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trigonelline SCHEMBL29561369 | 0.93 | USP2 (1.00) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL195666 | 0.93 | USP2 (1.00) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL31124498 | 0.91 | USP2 (0.96) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL678067 | 0.91 | USP2 (0.96) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL468365 | 0.91 | USP2 (0.96) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL1022662 | 0.91 | USP2 (0.96) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL5016191 | 0.87 | USP2 (0.89) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| Trigonelline SCHEMBL21177574 | 0.76 | USP2 (0.67) | USP2NNMTAPOBEC3AAPOBEC3GCA2 | |
| SCHEMBL700182 | 0.75 | NNMT (0.68) | USP2NNMTAPOBEC3AAPOBEC3GPABPC1 | |
| Trigonelline SCHEMBL679317 | 0.75 | NNMT (0.68) | USP2NNMTAPOBEC3AAPOBEC3GPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082433-A1 | METABOLOMICS-BASED BIOMARKERS FOR LUNG FUNCTION | LINEAGEN, INC. (US) | 2011-07-07 | — | — | WO | claimed |
| US-9823204-B2 | Metabolomics-based biomarkers for lung function | LINEAGEN, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20130149388-A1 | METABOLOMICS-BASED BIOMARKERS FOR LUNG FUNCTION | JGB COLLATERAL, LLC | 2013-06-13 | — | — | US | disclosed |
| WO-2011082433-A1 | METABOLOMICS-BASED BIOMARKERS FOR LUNG FUNCTION | LINEAGEN, INC. (US) | 2011-07-07 | — | — | WO | disclosed |