Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281113 | 0.87 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL38662511 | 0.85 | THRB (0.41) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11129092 | 0.76 | THRB (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL124287 | 0.75 | THRB (0.61) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16744077 | 0.75 | THRB (0.61) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16739318 | 0.74 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2466488 | 0.73 | THRB (0.59) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL30168585 | 0.72 | TSHR (0.40) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9270782 | 0.72 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16739333 | 0.71 | TSHR (0.53) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723301-B1 | POLYMERIZABLE ANTIBACTERIAL/ANTIMICROBIAL RESINS AND USE IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2020-03-04 | — | — | EP | disclosed |