Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679555 | 0.94 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4TRPA1PPARG | |
| SCHEMBL8229348 | 0.83 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4MAOBPPARG | |
| SCHEMBL20714984 | 0.79 | SLC6A2 (0.88) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3940696 | 0.78 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4TRPA1PPARG | |
| SCHEMBL11830999 | 0.78 | PPARG (0.51) | SLC6A2SLC6A3PPARGPPARAROCK2 | |
| SCHEMBL764989 | 0.75 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4ESR1LMNA | |
| SCHEMBL13802342 | 0.74 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4MAOBPPARG | |
| SCHEMBL8676494 | 0.73 | TRPA1 (0.47) | SLC6A2SLC6A3TRPA1PPARGALOX15 | |
| SCHEMBL2326795 | 0.73 | SLC6A2 (0.64) | SLC6A2SLC6A3SLC6A4PPARGPPARA | |
| SCHEMBL19342839 | 0.72 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934326-B2 | Peripheral modifications on pocket-redesigned vancomycin analogs synergistically improve antimicrobial potency and durability | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-03-02 | — | — | US | disclosed |
| US-20200071359-A1 | PERIPHERAL MODIFICATIONS ON POCKET-REDESIGNED VANCOMYCIN ANALOGS SYNERGISTICALLY IMPROVE ANTIMICROBIAL POTENCY AND DURABILITY | THE SCRIPPS RESEARCH INSTITUTE | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934326-B2 | Peripheral modifications on pocket-redesigned vancomycin analogs synergistically improve antimicrobial potency and durability | DDOST, DNPEP, AAAS | SLC6A2 3483/4885SLC6A3 1911/4885SLC6A4 2422/4885 |
| US-20200071359-A1 | PERIPHERAL MODIFICATIONS ON POCKET-REDESIGNED VANCOMYCIN ANALOGS SYNERGISTICALLY IMPROVE ANTIMICROBIAL POTENCY AND DURABILITY | DDOST, DNPEP, AAAS | SLC6A2 3483/4885SLC6A3 1911/4885SLC6A4 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.