Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783122 | 0.88 | LMNA (0.70) | ABCB1POLBLMNAMAPTGAA | |
| SCHEMBL23294736 | 0.84 | ABCB1 (0.69) | ABCB1POLBLMNAMAPTGAA | |
| SCHEMBL7934313 | 0.82 | MAPT (0.79) | POLBLMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL7936656 | 0.81 | NTRK1 (0.72) | LMNAMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL20337820 | 0.81 | ABCB1 (1.00) | ABCB1POLBLMNAMAPTGAA | |
| SCHEMBL7932253 | 0.80 | LMNA (0.71) | POLBLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL20337825 | 0.80 | ABCB1 (1.00) | ABCB1POLBLMNAMAPTGAA | |
| SCHEMBL7934316 | 0.77 | MAPT (0.61) | POLBLMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16904613 | 0.77 | ABCB1 (0.73) | ABCB1POLBLMNAMAPTGAA | |
| SCHEMBL20337833 | 0.77 | ABCB1 (1.00) | ABCB1POLBLMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11013739-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | SOUTHERN METHODIST UNIVERSITY (US) | 2021-05-25 | — | — | US | disclosed |
| US-20210134398-A1 | Combinatorial Chemistry Computational System and Enhanced Selection Method | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-05-06 | — | — | US | disclosed |
| US-20210134398-A1 | Combinatorial Chemistry Computational System and Enhanced Selection Method | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-05-06 | — | — | US | disclosed |
| US-20200069687-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | SOUTHERN METHODIST UNIVERSITY | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069687-A1 | Inhibitors of Multidrug Resistance Transporter P-Glycoprotein | ABCC1, ABCB1, SLC47A2 | ABCB1 2/4885POLB 3510/4885LMNA 3441/4885 |
| US-11013739-B2 | Inhibitors of multidrug resistance transporter p-glycoprotein | ABCC1, ABCB1, SLC47A2 | ABCB1 2/4885POLB 3510/4885LMNA 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.