Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092306 | 0.88 | PPARG (1.00) | PPARGALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL21783143 | 0.88 | PPARG (1.00) | PPARGALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL10492269 | 0.87 | NPSR1 (0.73) | PPARGKMT2AMEN1APP | |
| SCHEMBL10492261 | 0.87 | NPSR1 (0.73) | PPARGKMT2AMEN1APP | |
| SCHEMBL10492239 | 0.87 | MAPT (0.79) | MAPTALDH1A1NCOA3MAPK1 | |
| SCHEMBL10492233 | 0.87 | MAPT (0.79) | MAPTALDH1A1NCOA3MAPK1 | |
| SCHEMBL20534340 | 0.87 | MAPT (0.79) | MAPTALDH1A1NCOA3MAPK1 | |
| SCHEMBL14407429 | 0.84 | MAPT (0.70) | MAPTALDH1A1NCOA3MAPK1MCHR1 | |
| SCHEMBL12793841 | 0.84 | MAPT (0.77) | MAPTALDH1A1NCOA3MAPK1KMT2A | |
| SCHEMBL5746953 | 0.83 | PPARG (0.73) | PPARGALDH1A1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2020-03-05 | — | — | US | disclosed |
| CN-110621315-A | Heterocyclic inhibitors of lysine biosynthesis via the diaminopimelic acid pathway | 拉筹伯大学 | 2019-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | DDC, ODC1, DDT | PPARG 3668/4885MAPT 3729/4885ALDH1A1 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.