Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22778992 | 0.92 | KDM4E (0.52) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL21783269 | 0.88 | KDM4E (0.51) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL23197070 | 0.80 | KDM4E (0.54) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL26931416 | 0.77 | CACNA1F (0.65) | POLBKCNH2CACNA1FMAPK1CACNA1D | |
| SCHEMBL22778993 | 0.77 | KCNH2 (0.62) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL21074735 | 0.76 | KDM4E (0.49) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL5003903 | 0.75 | KDM4E (0.75) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL26932000 | 0.74 | KDM4E (0.47) | KDM4EHPGDALDH1A1LMNACYP2C19 | |
| SCHEMBL21074775 | 0.72 | MEN1 (0.65) | KDM4EHPGDALDH1A1LMNAPOLB | |
| SCHEMBL8564558 | 0.72 | KCNH2 (0.57) | KDM4EHPGDALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |