Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783201 | 0.92 | KDM4E (0.49) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL23197070 | 0.88 | KDM4E (0.54) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL26931416 | 0.84 | CACNA1F (0.65) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL21074735 | 0.83 | KDM4E (0.49) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL26932000 | 0.81 | KDM4E (0.47) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL8572213 | 0.81 | KCNH2 (0.57) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL8564558 | 0.81 | KCNH2 (0.57) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL8569402 | 0.81 | KCNH2 (0.57) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL21783269 | 0.80 | KDM4E (0.51) | KDM4EHPGDALDH1A1LMNAKCNH2 | |
| SCHEMBL9372691 | 0.80 | KCNH2 (0.60) | KDM4EHPGDALDH1A1LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2020-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | KDM4E 3437/4885HPGD 266/4885ALDH1A1 2346/4885 |
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | KDM4E 3437/4885HPGD 266/4885ALDH1A1 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.