Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168335 | 0.92 | LTA4H (0.88) | LTA4HKCNH2 | |
| SCHEMBL2168343 | 0.92 | LTA4H (0.88) | LTA4HKCNH2 | |
| SCHEMBL14093039 | 0.92 | LTA4H (0.88) | LTA4HKCNH2 | |
| SCHEMBL2169295 | 0.90 | LTA4H (0.76) | LTA4HKCNH2 | |
| SCHEMBL2169267 | 0.88 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL2169688 | 0.86 | LTA4H (0.78) | LTA4HKCNH2 | |
| SCHEMBL2168100 | 0.83 | LTA4H (0.82) | LTA4HKCNH2 | |
| SCHEMBL4693301 | 0.82 | LTA4H (0.88) | LTA4HKCNH2 | |
| SCHEMBL4693297 | 0.82 | LTA4H (0.88) | LTA4HKCNH2 | |
| SCHEMBL4998126 | 0.80 | LTA4H (0.80) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4726238-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| EP-1660492-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005012297-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | WO | claimed |