Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.55 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21953942 | 0.87 | ITGAV (0.41) | ITGAVITGB6ITGB3ITGB5ITGA2B | |
| SCHEMBL25799526 | 0.86 | ITGAV (0.40) | ITGAVITGB6 | |
| SCHEMBL31075819 | 0.84 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB8 | |
| SCHEMBL31075783 | 0.84 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB8 | |
| SCHEMBL31075708 | 0.84 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB8 | |
| SCHEMBL21777604 | 0.84 | GPR119 (0.39) | ITGAVITGB6 | |
| SCHEMBL21777605 | 0.84 | GPR119 (0.39) | ITGAVITGB6 | |
| SCHEMBL21777433 | 0.84 | ITGAV (0.54) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL21777434 | 0.84 | ITGAV (0.54) | ITGAVITGB6ITGB3ITGB5ITGB1 | |
| SCHEMBL21856588 | 0.83 | ITGAV (0.39) | ITGAVITGB6ITGB3ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047208-A1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |