Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 3/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981473 | 0.83 | CES2 (0.56) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL1004064 | 0.81 | HDAC6 (0.70) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL355600 | 0.79 | HDAC6 (0.71) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL15495188 | 0.78 | GAA (0.48) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL38657509 | 0.78 | HDAC1 (0.47) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL29055361 | 0.78 | HDAC6 (0.46) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL1005961 | 0.77 | HDAC6 (0.43) | HDAC6HDAC1HDAC8HDAC2PLAU | |
| SCHEMBL4478521 | 0.77 | HDAC8 (0.60) | HDAC6HDAC8HDAC2PLAUCA2 | |
| SCHEMBL23183311 | 0.76 | HDAC6 (0.58) | HDAC6HDAC1GAAHDAC8HDAC2 | |
| SCHEMBL1002234 | 0.76 | HDAC6 (0.44) | HDAC6HDAC1GAAHDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039917-A1 | EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION | JANSSEN PHARMACEUTICA NV (BE) | 2023-02-09 | — | — | US | disclosed |
| US-10703080-B2 | Film for medicine packaging and method of preparing the same | Sichuan Huili Industry Co., Ltd. (CN) | 2020-07-07 | — | — | US | disclosed |
| US-10703835-B2 | Hyperbranched cationic mussel-imitated polymer and method of preparing the same | Sichuan Huili Industry Co., Ltd. (CN) | 2020-07-07 | — | — | US | disclosed |
| US-20200070485-A1 | FILM FOR MEDICINE PACKAGING AND METHOD OF PREPARING THE SAME | Sichuan Huili Industry Co., Ltd. (CN) | 2020-03-05 | — | — | US | disclosed |
| US-20200071433-A1 | HYPERBRANCHED CATIONIC MUSSEL-IMITATED POLYMER AND METHOD OF PREPARING THE SAME | Sichuan Huili Industry Co., Ltd. (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039917-A1 | EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION | BMI1, MLLT1, SUZ12 | HDAC6 915/4885HDAC1 245/4885GAA 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.