Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21784366 | 0.79 | KDM1A (0.38) | KDM1AJAK2JAK1 | |
| SCHEMBL21775669 | 0.76 | JAK1 (0.42) | JAK2JAK1 | |
| SCHEMBL21320729 | 0.72 | KDM1A (0.50) | KDM1A | |
| SCHEMBL21320568 | 0.69 | KDM1A (0.62) | KDM1A | |
| SCHEMBL254096 | 0.67 | KMT2A (0.40) | KMT2A | |
| SCHEMBL25642115 | 0.66 | — | — | |
| SCHEMBL9040831 | 0.66 | KDM1A (0.41) | KDM1A | |
| SCHEMBL6926702 | 0.65 | KDM4E (0.35) | KMT2A | |
| SCHEMBL21320628 | 0.65 | KDM1A (0.52) | KDM1A | |
| SCHEMBL18820103 | 0.64 | KDM1A (0.66) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047198-A1 | SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME | INCYTE CORPORATION (US) | 2020-03-05 | — | — | WO | disclosed |