Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180835 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2177671 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2179458 | 0.77 | SMN1; SMN2 (0.36) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2179931 | 0.77 | KDM4E (0.32) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2180145 | 0.74 | SMN1; SMN2 (0.31) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2178185 | 0.74 | — | — | |
| SCHEMBL2179831 | 0.73 | HTR2A (0.31) | — | |
| SCHEMBL2177934 | 0.73 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL2178772 | 0.73 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL697959 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | KDM4E 4261/4885ALDH1A1 2095/4885TDP1 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.