PRDX1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL22822299	1.00	19/20
SCHEMBL22822305	1.00	19/20
SCHEMBL22822302	0.85	19/20
SCHEMBL22822306	1.00	18/20
SCHEMBL22822454	1.00	18/20
SCHEMBL18781883	0.83	18/20
SCHEMBL22010609	0.68	18/20
SCHEMBL22822210	1.00	17/20
SCHEMBL22822300	1.00	17/20
SCHEMBL22822311	1.00	17/20
SCHEMBL22822453	1.00	17/20
SCHEMBL22822296	1.00	16/20
SCHEMBL18781890	0.80	16/20
SCHEMBL22822200	0.72	16/20
SCHEMBL22010596	0.67	16/20
SCHEMBL23093885	0.57	16/20
SCHEMBL23093887	0.56	16/20
SCHEMBL22010877	0.63	15/20
SCHEMBL18781880	0.77	13/20
SCHEMBL18781888	0.77	13/20

Clinical trials — most relevant to PRDX1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Role of Vitamin E in Gaucher Disease Patients	PHASE3	COMPLETED
Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy	PHASE3	RECRUITING
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept	PHASE3	COMPLETED
Cysteine Supplementation in Critically Ill Neonates	PHASE2/PHASE3	UNKNOWN
Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients	PHASE3	UNKNOWN
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Beneficial Effect of Silymarin in Ulcerative Colitis	PHASE2	RECRUITING
Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial	PHASE2	COMPLETED
A Supervised Nutritional Program in Pregnancies and NF-κB Expression in Placenta	PHASE1	COMPLETED
Electrophilic Fatty Acid Derivatives in Asthma	PHASE1	COMPLETED
Clinical and Biochemical Assessment of the Effect of Topical Use of Coenzyme Q10 Versus Topical Corticosteroid in Management of Symptomatic Oral Lichen Planus: Randomized Controlled Clinical Trial	PHASE1	UNKNOWN
Antioxidant Signature in Adult Patients With Phenylketonuria	nan	COMPLETED
IVF Outcome in Polycystic Ovary Syndrome Patients	nan	UNKNOWN
Effect of Protein on Endoplasmic Reticulum Stress	nan	NOT_YET_RECRUITING
Thiol/Disulphide Homeostasis in Unexplained Infertility	nan	COMPLETED
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.	nan	COMPLETED
Personalizing Preterm Neonatal Transfusions With Fetal Hemoglobin-Enriched Cord Blood	nan	NOT_YET_RECRUITING
Role of Nox2 in CNI-induced Renal Fibrosis	nan	COMPLETED
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Protecting Autologous Free Flaps From Ischemia/Reperfusion Damage With Cold Storage.	nan	NOT_YET_RECRUITING
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Consumption of Apple Juice in Hemodialysis Patients	nan	COMPLETED
Evaluation of Mitochondrial Enzyme Activity in Cesarean Section Patients	nan	UNKNOWN
Effects of Oral Antioxidant Cocktail in Cardiovascular Disease Patients	nan	WITHDRAWN
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults	nan	COMPLETED
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People	nan	UNKNOWN
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome	nan	ACTIVE_NOT_RECRUITING
Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse	nan	ACTIVE_NOT_RECRUITING
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis	nan	NOT_YET_RECRUITING
Identification of Serum Level of Glutathione Peroxidase 4	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a PRDX1 binder may also engage these)

Protein	Name	Similarity
Q63716	—	1.000	Q63716 →
Q5E947	—	1.000	Q5E947 →
Q6B4U9	—	1.000	Q6B4U9 →
Q9JKY1	—	1.000	Q9JKY1 →
Q90384	—	1.000	Q90384 →
P0CB50	—	0.999	P0CB50 →
P35704	—	0.999	P35704 →
P35700	—	0.997	P35700 →
Q9V3P0	—	0.997	Q9V3P0 →
A0A0K3AUJ9	—	0.997	A0A0K3AUJ9 →
Q8T6C4	—	0.997	Q8T6C4 →
Q61171	—	0.997	Q61171 →
Q6DV14	—	0.997	Q6DV14 →
Q9NL98	—	0.995	Q9NL98 →
Q17172	—	0.995	Q17172 →
Q26695	—	0.994	Q26695 →
Q8K3U7	—	0.993	Q8K3U7 →
PRDX2	Peroxiredoxin-2	0.992	landscape →
Q2PFZ3	—	0.992	Q2PFZ3 →
P0C5C8	—	0.991	P0C5C8 →
Q9BGI3	—	0.991	Q9BGI3 →
Q5RC63	—	0.991	Q5RC63 →
P56876	—	0.990	P56876 →
O74887	—	0.990	O74887 →
Q6W8Q2	—	0.990	Q6W8Q2 →
Q2YVK2	—	0.990	Q2YVK2 →
Q04120	—	0.990	Q04120 →
P23161	—	0.990	P23161 →
P0A0B7	—	0.989	P0A0B7 →
Q96468	—	0.989	Q96468 →