Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20487757 | 0.89 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 | |
| SCHEMBL20481347 | 0.89 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 | |
| SCHEMBL19448351 | 0.88 | HPGD (0.38) | CYP4F2CYP4A11USP2SMN1; SMN2CNR2 | |
| SCHEMBL18688892 | 0.88 | HPGD (0.38) | CYP4F2CYP4A11USP2SMN1; SMN2CNR2 | |
| SCHEMBL20487725 | 0.88 | CYP4F2 (0.40) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 | |
| SCHEMBL20480989 | 0.88 | CYP4F2 (0.40) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 | |
| SCHEMBL23579455 | 0.85 | CYP4F2 (0.43) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 | |
| SCHEMBL26044480 | 0.83 | CYP4F2 (0.42) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 | |
| SCHEMBL19448348 | 0.82 | HPGD (0.40) | CYP4F2CYP4A11USP2SMN1; SMN2USP30 | |
| SCHEMBL21216177 | 0.81 | USP2 (0.42) | CYP4F2CYP4A11USP2SMN1; SMN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827621-B2 | Inhibitors of (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11739087-B2 | Inhibiting (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2020047239-A1 | INHIBITING αV β6 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827621-B2 | Inhibitors of (α-v)(β-6) integrin | ITGB6, ITGA6, ITGAV | CYP4F2 4202/4885CYP4A11 4609/4885USP2 4364/4885 |
| US-11739087-B2 | Inhibiting (α-v)(β-6) integrin | ITGB6, ITGA6, ITGAV | CYP4F2 4096/4885CYP4A11 4600/4885USP2 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.