Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767410 | 0.88 | CFTR (0.45) | ALDH1A1KDM4ELMNAOXTRAVPR1A | |
| SCHEMBL31071992 | 0.88 | CFTR (0.45) | ALDH1A1KDM4ELMNAOXTRAVPR1A | |
| SCHEMBL29429452 | 0.85 | CFTR (0.42) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL31072015 | 0.85 | CFTR (0.42) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL21767551 | 0.85 | CFTR (0.42) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL21780595 | 0.85 | CFTR (0.42) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL21767420 | 0.85 | CFTR (0.42) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL31071934 | 0.85 | CFTR (0.42) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL21767595 | 0.79 | PTGDR2 (0.40) | KDM4ELMNACFTRHPGDCYP1A2 | |
| SCHEMBL21767405 | 0.79 | PTGDR2 (0.40) | KDM4ELMNACFTRHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047239-A1 | INHIBITING αV β6 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |