Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 8/20 | 0.45 |
| ▸ | CCR2 | P41597 | 8/20 | 0.45 |
| ▸ | CCR4 | P51679 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023638 | 0.78 | KMT2A (0.46) | KMT2ACYP3A4CYP2C9CYP2C19MAOA | |
| SCHEMBL28761316 | 0.76 | PSEN1 (0.37) | KMT2ACCR1CCR2CCR4CYP3A4 | |
| SCHEMBL14370854 | 0.72 | KDM4E (0.50) | KMT2ACCR1CCR2CCR4CYP3A4 | |
| SCHEMBL5301838 | 0.72 | CCR1 (0.54) | CCR1CCR2CCR4CYP3A4CYP2C9 | |
| SCHEMBL8908893 | 0.72 | CYP2C9 (0.54) | KMT2ACYP3A4CYP2C9CYP2C19MAOA | |
| SCHEMBL25934781 | 0.71 | CYP19A1 (0.46) | CCR1CCR2CCR4PSEN1PSEN2 | |
| SCHEMBL11621292 | 0.71 | IDO1 (0.65) | CYP3A4CYP2C9CYP2C19MAOAMAOB | |
| SCHEMBL10851275 | 0.70 | ALDH1A1 (0.53) | KMT2ACYP19A1MAPK1LMNAHTT | |
| SCHEMBL9657759 | 0.70 | CYP3A4 (0.40) | CCR1CCR2CCR4CYP3A4CYP2C9 | |
| SCHEMBL21784834 | 0.68 | CYP3A4 (0.46) | CCR1CCR2CCR4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200072711-A1 | FLUORESCENT ENDOPLASMIC RETICULUM TRACKERS FOR LIVE CELL IMAGING OF PATHOGENIC YEAST | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2020-03-05 | — | — | US | disclosed |