Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 19/20 | 0.54 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402960 | 0.90 | ITGAV (0.62) | ITGAVITGB6ITGB3ITGB5 | |
| SCHEMBL21351206 | 0.85 | ITGAV (0.47) | ITGAVITGB6ITGB3ITGB5CXCR4 | |
| SCHEMBL21329049 | 0.84 | ITGAV (0.56) | ITGAVITGB6ITGB3ITGB5CXCR4 | |
| SCHEMBL29416481 | 0.84 | ITGAV (0.56) | ITGAVITGB6ITGB3ITGB5CXCR4 | |
| SCHEMBL7797597 | 0.83 | ITGAV (0.51) | ITGAVITGB6ITGB3ITGB5CXCR4 | |
| SCHEMBL27130457 | 0.83 | ITGAV (0.60) | ITGAVITGB6ITGB3 | |
| SCHEMBL30673942 | 0.83 | ITGAV (0.55) | ITGAVITGB6ITGB3ITGB5 | |
| SCHEMBL23816697 | 0.82 | ITGAV (0.50) | ITGAVITGB6ITGB3ITGB5CXCR4 | |
| SCHEMBL14655007 | 0.82 | CXCR4 (0.51) | ITGAVITGB6ITGB3ITGB5CXCR4 | |
| SCHEMBL4714404 | 0.81 | ITGB3 (0.52) | ITGAVITGB6ITGB3ITGB5CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047239-A1 | INHIBITING αV β6 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2020-03-05 | — | — | WO | disclosed |