SCHEMBL2178508

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3134382	0.99	KDM4E (0.41)	KDM4EDRD2ALDH1A1MAPTHPGD
	SCHEMBL2151205	0.85	KDM4E (0.44)	KDM4EALDH1A1MAPTSIGMAR1LMNA
	SCHEMBL2150649	0.84	KDM4E (0.46)	KDM4EALDH1A1MAPTSIGMAR1LMNA
	SCHEMBL2173930	0.80	MALT1 (0.36)	DRD2GAANQO2CA1CA2
	SCHEMBL3124904	0.79	CYP3A4 (0.38)	KDM4EDRD2GAANQO2MALT1
	SCHEMBL2151028	0.79	KDM4E (0.43)	KDM4EALDH1A1MAPTLMNATSHR
	SCHEMBL3128178	0.79	USP30 (0.39)	KDM4EDRD2PARP1NQO2CA1
	SCHEMBL3388612	0.78	CA1 (0.43)	KDM4EDRD2ALDH1A1MAPTHPGD
	SCHEMBL2150964	0.78	KDM4E (0.44)	KDM4EALDH1A1MAPTLMNATSHR
	SCHEMBL2178511	0.78	CA1 (0.40)	KDM4EDRD2ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.