⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25247012 | 0.79 | — | — | |
| SCHEMBL246368 | 0.75 | — | — | |
| SCHEMBL31586523 | 0.75 | — | — | |
| SCHEMBL31259503 | 0.75 | — | — | |
| SCHEMBL10034998 | 0.75 | — | — | |
| SCHEMBL13202779 | 0.75 | — | — | |
| SCHEMBL10161873 | 0.75 | — | — | |
| SCHEMBL4145389 | 0.75 | — | — | |
| SCHEMBL14594131 | 0.75 | — | — | |
| SCHEMBL2183234 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2841 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751461-A | PKMYT1 inhibitor and preparation method and application thereof | 中国药科大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119504740-A | New preparation method of palbociclin | 江苏权正检验检测有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119059982-A | Hydroxamic acid Mer/HDAC double-target inhibitor and preparation method and application thereof | 河北科技大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118724825-A | Mer/HDAC double-target inhibitor and application thereof in preparation of antitumor drugs | 河北科技大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118027006-A | 2, 4-Diaminopyrimidine derivative and preparation method and application thereof | 温州医科大学附属第一医院 | 2024-05-14 | — | — | CN | claimed |
| CN-117903147-A | Preparation method of treasipril and intermediate thereof | 沈阳药科大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117069663-B | Synthesis method of rebaudinib intermediate V and synthesis method of rebaudinib | 四川维亚本苑生物科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117069663-A | Synthesis method of rebaudinib intermediate V and synthesis method of rebaudinib | 四川维亚本苑生物科技有限公司 | 2023-11-17 | — | — | CN | claimed |
| US-20230295144-A1 | 2-polysubstituted aromatic ring-pyrimidine derivatives, preparation and medical application thereof | UNIV ZHEJIANG (CN) | 2023-09-21 | — | — | US | claimed |
| CN-112920182-B | Preparation method of palbociclib | 上海天慈国际药业有限公司 | 2023-08-01 | — | — | CN | claimed |
| US-10822327-B2 | 2-substituted aromatic ring-pyrimidine derivative and preparation and application thereof | ZHEJIANG UNIVERSITY (CN) | 2020-11-03 | — | — | US | claimed |
| CN-111233834-A | FAK-targeting compound and markers thereof, and preparation methods and applications of FAK-targeting compound and markers | 北京师范大学 | 2020-06-05 | — | — | CN | claimed |
| EP-3530657-A1 | 2-POLYSUBSTITUTED AROMATIC RING-PYRIMIDINE DERIVATIVE AND PREPARATION AND MEDICAL USE | Zhejiang University (CN) | 2019-08-28 | — | — | EP | claimed |
| EP-3530656-A1 | 2-SUBSTITUTED AROMATIC RING-PYRIMIDINE DERIVATIVE, AND PREPARATION AND APPLICATION THEREOF | Zhejiang University (CN) | 2019-08-28 | — | — | EP | claimed |
| CN-109721547-A | A kind of preparation method of intermediate that treating breast cancer medicines Pa Boxini | 陈欣 | 2019-05-07 | — | — | CN | claimed |
| CN-109206375-A | A kind of 5 cyclosubstituted 2,4- diaminopyrimidines with benzene glycinol class formation, its preparation and purposes | 中国科学院上海药物研究所 | 2019-01-15 | — | — | CN | claimed |
| US-7825128-B2 | Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs | BAYER SCHERING PHARMA AG (DE) | 2010-11-02 | — | — | US | claimed |
| EP-1963282-A1 | SULFOXIMINE-SUBSTITUTED PYRIMIDINES , THEIR PREPARATION AND USE AS DRUGS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | claimed |
| US-20070232632-A1 | Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-10-04 | — | — | US | claimed |
| WO-2007071455-A1 | SULFOXIMINE-SUBSTITUTED PYRIMIDINES , THEIR PREPARATION AND USE AS DRUGS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | claimed |