Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21785278 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL26755843 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL435143 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL21785533 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL26756604 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL21785849 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL9802586 | 0.76 | PKN1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL21284842 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL21040050 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL19706853 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047184-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES | ARRAY BIOPHARMA INC. (US) | 2020-03-05 | — | — | WO | disclosed |