SCHEMBL217861

SCHEMBL217861

[CH2]Cc1ccc(C)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20357980 0.97 IDO1 (0.50)
Magnesium Chloride Anhydrous SCHEMBL28474826 0.89 CYP1A2 (0.46)
SCHEMBL20302526 0.89 IDO1 (0.44)
SCHEMBL1803971 0.83 ESR1 (0.32)
SCHEMBL310520 0.77 CYP1A2 (0.56)
SCHEMBL840261 0.75 TP53 (0.50)
SCHEMBL1806452 0.75
SCHEMBL2451123 0.75 CYP1A2 (0.59)
SCHEMBL22092391 0.75 CYP1A2 (0.54)
SCHEMBL1149394 0.73 IDO1 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2739 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
CN-117799197-A Large-area electrochromic device and preparation method thereof 绍兴百立盛新材料科技有限公司 2024-04-02 CN claimed
CN-114901702-B Glycosaminoglycan derivative and application thereof 深圳市海普瑞药业集团股份有限公司 2024-01-09 CN claimed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP claimed
WO-2023055427-A1 SMALL MOLECULE ANTAGONISTS OF PF4 NEW YORK BLOOD CENTER, INC. (US) 2023-04-06 WO claimed
WO-2022245951-A1 INHIBITORS OF CDR1 FOR REVERSAL OF AZOLE DRUG RESISTANCE IN FUNGAL INFECTIONS UNM RAINFOREST INNOVATIONS (US) 2022-11-24 WO claimed
CN-115260834-A Sulfur-containing high-refractive-index ink composition and preparation method thereof 西安思摩威新材料有限公司 2022-11-01 CN claimed
CN-114901702-A Glycosaminoglycan derivative and application thereof 深圳市海普瑞药业集团股份有限公司 2022-08-12 CN claimed
EP-4015512-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2022-06-22 EP claimed
EP-2303331-B1 OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME ALCON INC (CH) 2022-01-26 EP claimed
US-4181733-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-01-01 US claimed
US-4167630-A Process for epimerizing beta-lactam antibiotic compounds, and related products MERCK & CO., INC. (US) 1979-09-11 US claimed
US-4138414-A 2-Phenoxy and 2-phenylthio anthraquinone disperse dyes SANDOZ LTD. (CH) 1979-02-06 US claimed
US-4107432-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-08-15 US claimed
US-4077962-A WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-07 US claimed
US-4058661-A 7-Diacyl cephalosporins MERCK & CO., INC. (US) 1977-11-15 US claimed
US-4053286-A ACYLATION MERCK & CO., INC. (US) 1977-10-11 US claimed
US-4051132-A Process for epimerizing beta-lactam antibiotic compounds by means of an acid quench MERCK & CO., INC. (US) 1977-09-27 US claimed
US-4024156-A Thiophene ethanolamines AMERICAN HOME PRODUCTS CORPORATION (US) 1977-05-17 US claimed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US claimed