SCHEMBL310520

SCHEMBL310520

[CH2]CCc1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
CYP2A6 P11509 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
IDO1 P14902 1/20 0.48
KCNH2 Q12809 2/20 0.45
HRH3 Q9Y5N1 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
ACHE P22303 1/20 0.44
IGF1R P08069 1/20 0.43
ALOX15 P16050 1/20 0.43
AGXT P21549 2/20 0.42
CHKA P35790 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
HRH1 P35367 1/20 0.39
FFAR1 O14842 1/20 0.39
DAO P14920 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22092391 0.97 CYP1A2 (0.54) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL2745550 0.85 GFER (0.42) CYP1A2CYP2A6TAAR1HRH3TDP1
SCHEMBL1119426 0.84 CYP1A2 (0.52) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL22092404 0.82 CYP1A2 (0.50) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL1119390 0.82 IGF1R (0.53) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL143961 0.82 CYP1A2 (0.68) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL11288839 0.82 CYP1A2 (0.68) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL1610894 0.80 IGF1R (0.52) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL7732435 0.80 IGF1R (0.52) CYP1A2CYP2A6TAAR1IDO1KCNH2
SCHEMBL11403376 0.80 IGF1R (0.52) CYP1A2CYP2A6TAAR1IDO1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567489-A Method for preparing C-2 boronated indole by boron tribromide mediated metal-free directional C-H boronation 上海毕得医药科技股份有限公司 2024-02-20 CN claimed
EP-3688124-B1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-25 EP claimed
EP-3688124-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2020-08-05 EP claimed
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-14 US claimed
CN-111386331-A Ester compound, lubricating oil composition containing same, and method for producing same 埃克森美孚化学专利公司 2020-07-07 CN claimed
WO-2019067061-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-04-04 WO claimed
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-04-04 US claimed
WO-2017199103-A1 BENZAMIDE COMPOUNDS AS ROR GAMMA MODULATORS GLENMARK PHARMACEUTICALS S.A. (CH) 2017-11-23 WO claimed
CN-103547611-B Polymer compound and light-emitting element formed using same 住友化学株式会社 2016-06-08 CN claimed
US-20130045942-A1 N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2013-02-21 US claimed
EP-0740652-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-11-06 EP claimed
EP-0740655-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-11-06 EP claimed
WO-1996033165-A1 DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-10-24 WO claimed
WO-1996033161-A1 DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-10-24 WO claimed
WO-1996006074-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-02-29 WO claimed
WO-1995019956-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-07-27 WO claimed
WO-1995019961-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-07-27 WO claimed
US-4648898-A DIAMINO-DIFLUOROMETHYLTHIOTRIAZINES SHIONOGI & CO., LTD. (JP) 1987-03-10 US claimed
US-4537890-A 2-(3,5-Substituted-2-pyridylalkylamino)-5-oxopyridylmethyl-4-pyrimidones useful as histamine H1 -antagonists SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1985-08-27 US claimed
US-3975361-A ETHER-SILOXANE BLOCK POLYMERIC STABILIZERS RHONE-POULENC S.A. (FR) 1976-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same ELOVL1, NOTUM, ELOVL5 CYP1A2 913/4885CYP2A6 1830/4885TAAR1 1228/4885
US-20130045942-A1 N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF ADORA2A, ADORA3, ADORA1 CYP1A2 367/4885CYP2A6 243/4885TAAR1 1309/4885
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same ELOVL1, NOTUM, ELOVL5 CYP1A2 913/4885CYP2A6 1830/4885TAAR1 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.