Chlormezanone

Chlormezanone

SCHEMBL217864

CN1C(=O)CCS(=O)(=O)C1c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
THRB P10828 1/20 1.00
APEX1 P27695 1/20 1.00
PMP22 Q01453 1/20 1.00
TSHR P16473 1/20 1.00
NFKB1 P19838 1/20 1.00
CYP2C19 P33261 1/20 1.00
SRD5A1 P18405 5/20 0.44
MDM2 Q00987 2/20 0.40
CHRNA7 P36544 1/20 0.37
KDM4E B2RXH2 3/20 0.36
HPGD P15428 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
SRD5A2 P31213 2/20 0.36
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
RAB9A P51151 1/20 0.34
HSD17B2 P37059 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlormezanone SCHEMBL117870 1.00 LMNA (1.00) LMNATHRBAPEX1PMP22TSHR
Dichlormezanone SCHEMBL2107746 0.84 LMNA (0.72) LMNATHRBAPEX1PMP22TSHR
Chlormezanone SCHEMBL28086474 0.82 LMNA (0.67) LMNATHRBAPEX1PMP22TSHR
Chlormezanone SCHEMBL20770956 0.78 LMNA (0.61) LMNATHRBAPEX1PMP22TSHR
SCHEMBL22781363 0.70 SRD5A1 (0.57) LMNATHRBAPEX1PMP22TSHR
SCHEMBL11479651 0.63 KMT2A (0.51) LMNATHRBAPEX1PMP22TSHR
SCHEMBL15972077 0.62 MDM2 (0.80) LMNATHRBAPEX1PMP22TSHR
SCHEMBL15972076 0.62 MDM2 (0.80) LMNATHRBAPEX1PMP22TSHR
SCHEMBL15989532 0.62 MDM2 (0.80) LMNATHRBAPEX1PMP22TSHR
SCHEMBL15972579 0.62 MDM2 (0.80) LMNATHRBAPEX1PMP22TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2288 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213593-A1 Use of Derivatives based on Sarsasapogenin Structure and Pharmaceutical Compositions thereof BEIJING PHYTOVENT PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2025-07-03 US claimed
CN-120025976-A Method for differentiating hematopoietic stem/progenitor cells into granulocytes 苏州血霁生物科技有限公司 2025-05-23 CN claimed
US-20250163379-A1 METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS HEMACELL BIOTECHNOLOGY INC. (CN) 2025-05-22 US claimed
WO-2025062440-A1 TOPICAL NANO-DISPERSION COMPOSITIONS AND THEIR PREPARATION THEREOF PULSE PHARMACEUTICALS PVT. LTD (IN) 2025-03-27 WO claimed
EP-4525870-A1 METHODS OF TREATING CUSHING'S SYNDROME AND LIVER DISORDERS, AND OF REDUCING LIVER TOXICITY OF OTHER DRUGS ADMINISTERED TO A PATIENT Corcept Therapeutics Incorporated (US) 2025-03-26 EP claimed
CN-119317433-A Methods for treating cushing's syndrome and liver disease and reducing hepatotoxicity of other drugs taken by patients 科赛普特治疗学股份有限公司 2025-01-14 CN claimed
EP-4477225-A1 USE OF SARSASAPOGENIN STRUCTURE-BASED DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF Beijing Phytovent Pharmaceutical Technology Co., Ltd. (CN) 2024-12-18 EP claimed
CN-118931541-A Tungsten/titanium nitride etching solution for avoiding intermetallic electrochemical corrosion effect 湖北兴福电子材料股份有限公司 2024-11-12 CN claimed
CN-118786209-A Method for differentiating hematopoietic stem/progenitor cells into NK cells 苏州血霁生物科技有限公司 2024-10-15 CN claimed
US-20240245659-A1 Methods of Treating Cushing's Syndrome and Liver Disorders, and of Reducing Liver Toxicity of Other Drugs Administered to a Patient CORCEPT THERAPEUTICS INCORPORATED (US) 2024-07-25 US claimed
EP-0209403-B1 PROCESS FOR PREPARING ULTRAFINE PARTICLES OF ORGANIC COMPOUNDS Research Development Corporation of Japan (JP) 1991-10-23 EP claimed
US-4913865-A Process for preparing ultrafine particles of organic compounds RESEARCH DEVELOPMENT CORP OF JAPAN (JP) 1990-04-03 US claimed
US-4780463-A CONTAINING PROPIONIC ACID COMPOUNDS ANALGESIC ASSOCIATES (US) 1988-10-25 US claimed
EP-0209403-A2 Process for preparing ultrafine particles of organic compounds Research Development Corporation of Japan (JP) 1987-01-21 EP claimed
EP-0205492-A1 ANALGESIC, ANTI-INFLAMMATORY AND SKELETAL MUSCLE RELAXANT COMPOSITIONS SUNSHINE, Abraham (US) 1986-12-30 EP claimed
WO-1986003681-A1 ANALGESIC, ANTI-INFLAMMATORY AND SKELETAL MUSCLE RELAXANT COMPOSITIONS SUNSHINE ABRAHAM 1986-07-03 WO claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed
US-4540602-A Process for the preparation of activated pharmaceutical compositions FREUND INDUSTRY COMPANY, LIMITED (JP) 1985-09-10 US claimed
US-4181719-A Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates STERLING DRUG INC. (US) 1980-01-01 US claimed
US-4175119-A Composition and method to prevent accidental and intentional overdosage with psychoactive drugs PORTER GARRY L 1979-11-20 US claimed