Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19830184 | 0.84 | LMNA (0.39) | TSHRSMN1; SMN2TDP1 | |
| SCHEMBL23956816 | 0.82 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1CA2MAPK1 | |
| SCHEMBL6910847 | 0.74 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1CA2MAPK1 | |
| SCHEMBL13859355 | 0.72 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1CA2MAPK1 | |
| SCHEMBL6250382 | 0.72 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1CA2MAPK1 | |
| SCHEMBL540777 | 0.72 | TSHR (0.39) | TSHRSMN1; SMN2 | |
| SCHEMBL20541343 | 0.69 | TSHR (0.48) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL20541342 | 0.69 | TSHR (0.48) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3846687 | 0.69 | — | — | |
| SCHEMBL22092215 | 0.68 | TSHR (0.52) | TSHRSMN1; SMN2CA2MAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9976103-B2 | Lubricating composition containing an antiwear agent | THE LUBRIZOL CORPORATION (US) | 2018-05-22 | — | — | US | claimed |
| US-9976103-B2 | Lubricating composition containing an antiwear agent | THE LUBRIZOL CORPORATION (US) | 2018-05-22 | — | — | US | disclosed |
| EP-2513269-B1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | LUBRIZOL CORP (US) | 2017-10-25 | — | — | EP | disclosed |
| US-20130172221-A1 | Lubricating Composition Containing an Antiwear Agent | THE LUBRIZOL CORPORATION (US) | 2013-07-04 | — | — | US | disclosed |
| EP-2513269-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | The Lubrizol Corporation (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011081835-A1 | LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT | THE LUBRIZOL CORPORATION (US) | 2011-07-07 | — | — | WO | disclosed |