Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17472748 | 0.81 | TSHR (0.35) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL1489359 | 0.79 | TSHR (0.33) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL28672178 | 0.75 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL11367727 | 0.74 | — | — | |
| SCHEMBL59826 | 0.71 | — | — | |
| SCHEMBL28693892 | 0.71 | — | — | |
| SCHEMBL3478304 | 0.70 | — | — | |
| SCHEMBL538268 | 0.69 | — | — | |
| SCHEMBL237880 | 0.69 | — | — | |
| SCHEMBL16767715 | 0.68 | ALDH1A1 (0.38) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043533-A1 | INTEGRIN ANTAGONISTS | Oxurion NV (BE) | 2020-03-05 | — | — | WO | disclosed |