Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 15/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140411 | 0.91 | L3MBTL1 (0.46) | L3MBTL1PDE5A | |
| SCHEMBL21787225 | 0.88 | L3MBTL1 (0.60) | L3MBTL1PDE5AAURKAPTGDR2 | |
| SCHEMBL24205908 | 0.87 | L3MBTL1 (0.44) | L3MBTL1PDE5APTGDR2 | |
| SCHEMBL20161255 | 0.87 | L3MBTL1 (0.41) | L3MBTL1PDE5AAURKA | |
| SCHEMBL21787238 | 0.87 | L3MBTL1 (0.49) | L3MBTL1PDE5APTGDR2 | |
| SCHEMBL21787236 | 0.85 | L3MBTL1 (0.47) | L3MBTL1PDE5AAURKAAURKB | |
| SCHEMBL21787195 | 0.85 | L3MBTL1 (0.44) | L3MBTL1PDE5AAURKA | |
| SCHEMBL20161279 | 0.84 | L3MBTL1 (0.37) | L3MBTL1PDE5A | |
| SCHEMBL21787287 | 0.82 | L3MBTL1 (0.45) | L3MBTL1PDE5A | |
| SCHEMBL24040769 | 0.81 | PDE5A (0.44) | L3MBTL1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071318-A1 | SGC STIMULATORS | GUCY1A2, GMPS, PDE2A | L3MBTL1 4698/4885PDE5A 12/4885AURKA 4737/4885 |
| US-11180493-B2 | SGC stimulators | GUCY1A2, GMPS, PDE2A | L3MBTL1 4698/4885PDE5A 12/4885AURKA 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.