SCHEMBL21788

SCHEMBL21788

CN(C)c1ccccc1-c1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.36
ALDH1A1 P00352 2/20 0.33
NSD2 O96028 1/20 0.33
EGFR P00533 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNN4 O15554 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353225 1.00 HTR6 (0.36) HTR6ALDH1A1NSD2EGFRLMNA
SCHEMBL29354371 1.00 HTR6 (0.36) HTR6ALDH1A1NSD2EGFRLMNA
SCHEMBL4988734 0.98 HTR6 (0.34) HTR6ALDH1A1NSD2EGFRLMNA
Bromide SCHEMBL1030113 0.97 HTR6 (0.35) HTR6ALDH1A1NSD2EGFRLMNA
SCHEMBL19469290 0.96 HTR6 (0.34) HTR6ALDH1A1NSD2EGFRLMNA
SCHEMBL28174897 0.94 HTR6 (0.33) HTR6KCNN4
SCHEMBL1030115 0.94 HTR6 (0.33) HTR6
SCHEMBL2296753 0.93 NPSR1 (0.33) HTR6ALDH1A1LMNAMAPTKCNN4
SCHEMBL2512861 0.91 HTR6 (0.32) HTR6
SCHEMBL3129527 0.88 HTR6 (0.36) HTR6ALDH1A1NSD2EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5122 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725945-A1 PREPARATION METHOD FOR FORMAMIDE COMPOUNDS Shanghai Senhui Medicine Co., Ltd. (CN) 2026-04-15 EP claimed
US-12577236-B2 Processes for preparation of Tezacaftor LAURUS LABS LIMITED (IN) 2026-03-17 US claimed
US-20250206723-A1 METHODS AND PROCESSES FOR THE PREPARATION OF MCT4 INHIBITORS Vettore, LLC 2025-06-26 US claimed
WO-2025081982-A1 PREPARATION METHOD FOR FINERENONE KEY INTERMEDIATE 山东诚创蓝海医药科技有限公司 2025-04-24 WO claimed
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same YALE UNIVERSITY (US) 2025-02-25 US claimed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 US claimed
WO-2024251227-A1 PREPARATION METHOD FOR FORMAMIDE COMPOUNDS 上海森辉医药有限公司 2024-12-12 WO claimed
US-12122788-B2 Process of making CFTR modulators VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-10-22 US claimed
US-20240327355-A1 METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US claimed
US-20240300922-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION 2024-09-12 US claimed
EP-1383734-A2 COMPOUNDS USEFUL AS INTERMEDIATES FOR 4-AMINOQUINOLINE DERIVATIVES Pfizer Products Inc. (US) 2004-01-28 EP claimed
US-6664396-B1 Reacting N,N'-unsubstituted quinacridone compound with haloaryl compound in presence of metal or metal compound to arylate N and N' positions and form corresponding N,N'-diarylquinacridone compound EASTMAN KODAK COMPANY 2003-12-16 US claimed
WO-2002088069-A9 COMPOUNDS USEFUL AS INTERMEDIATES FOR 4-AMINOQUINOLINE DERIVATIVES PFIZER PROD INC (US) 2003-12-04 WO claimed
EP-1345889-A1 METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO G]QUINOLINE-3-CARBONITRILES AND BENZO G]QUINAZOLINES Wyeth (US) 2003-09-24 EP claimed
US-20030144506-A1 Processes for the preparation of substituted bicyclic derivatives for the treatment of abnormal cell growth PFIZER INC. 2003-07-31 US claimed
US-20030060624-A1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic componunds PFIZER INC. 2003-03-27 US claimed
US-20020177716-A1 Intermediates of CETP inhibitors DAMON DAVID B (US) 2002-11-28 US claimed
WO-2002088069-A2 COMPOUNDS USEFUL AS INTERMEDIATES FOR 4-AMINOQUINOLINE DERIVATIVES PFIZER PRODUCTS INC. (US) 2002-11-07 WO claimed
WO-2002053528-A1 METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES WYETH (US) 2002-07-11 WO claimed
US-20020091273-A1 Method for the regioselective preparation of substituted benzo[g]quinoline3-carbonitriles and benzo[g]quinazolines AMERICAN HOME PRODUCTS CORPORATION 2002-07-11 US claimed