Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12510871 | 0.81 | EPHX1 (0.44) | CYP2C19SMN1; SMN2ALDH1A1POLBCYP2C9 | |
| SCHEMBL6571608 | 0.80 | SLC6A4 (0.52) | SMN1; SMN2ALDH1A1TSHRLTA4HL3MBTL1 | |
| SCHEMBL6580484 | 0.79 | NQO1 (0.64) | CYP2C19SMN1; SMN2ALDH1A1POLBCYP2C9 | |
| SCHEMBL21787935 | 0.78 | CYP1A2 (0.57) | CYP2C19ALDH1A1POLBCYP2C9KMT2A | |
| SCHEMBL23900923 | 0.76 | NQO1 (0.58) | CYP2C19SMN1; SMN2ALDH1A1POLBCYP2C9 | |
| SCHEMBL27586168 | 0.76 | NQO1 (0.58) | CYP2C19SMN1; SMN2ALDH1A1POLBCYP2C9 | |
| SCHEMBL5018760 | 0.74 | NQO1 (0.61) | NQO1TSHRTDP1ACACB | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.73 | NQO1 (1.00) | SMN1; SMN2ALDH1A1POLBNQO1TSHR | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.73 | NQO1 (1.00) | SMN1; SMN2ALDH1A1POLBNQO1TSHR | |
| SCHEMBL21186074 | 0.73 | EPHX1 (0.39) | CYP2C19SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20200069814-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069814-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | CD4, MCL1, CCNB1 | CYP2C19 1661/4885SMN1; SMN2 1688/4885ALDH1A1 1130/4885 |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | CYP2C19 4151/4885SMN1; SMN2 4335/4885ALDH1A1 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.