Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.61 |
| ▸ | ACACB | O00763 | 11/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146399 | 0.94 | NQO1 (0.54) | NQO1ACACBSIGMAR1TSHRTDP1 | |
| SCHEMBL25443770 | 0.84 | TDP1 (0.48) | ACACBSIGMAR1TDP1 | |
| SCHEMBL13003915 | 0.83 | NQO1 (0.56) | NQO1ACACBSIGMAR1TSHRTDP1 | |
| SCHEMBL16845224 | 0.83 | NQO1 (0.56) | NQO1ACACB | |
| SCHEMBL5018832 | 0.83 | KDM4E (0.53) | ACACBTSHR | |
| SCHEMBL13889410 | 0.83 | LMNA (0.54) | ACACB | |
| SCHEMBL2553015 | 0.83 | SLC6A4 (0.66) | NQO1 | |
| SCHEMBL24973088 | 0.83 | NQO1 (0.56) | NQO1ACACBSIGMAR1TSHRTDP1 | |
| SCHEMBL2553013 | 0.83 | SLC6A4 (0.66) | NQO1 | |
| SCHEMBL15307617 | 0.83 | SLC2A1 (0.49) | ACACBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5462923-A | For imparting aroma to, or augmenting or enhancing aroma of, various consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1995-10-31 | — | — | US | claimed |
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | SEDERMA (FR) | 2024-07-04 | — | — | US | disclosed |
| US-11059826-B2 | Pteridinone compounds and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-07-13 | — | — | US | disclosed |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| US-20190322673-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2019-10-24 | — | — | US | disclosed |
| CN-105793039-B | Surface protective film | 三菱化学株式会社 | 2019-09-06 | — | — | CN | disclosed |
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER | 2019-08-08 | — | — | US | disclosed |
| EP-3072875-B1 | ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-3072875-B1 | ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-13 | — | — | EP | disclosed |
| CN-103571354-B | Pressure-sensitive adhesive sheet, electrically or electronically bulking block laminate and optical member laminate | 日东电工株式会社 | 2018-05-04 | — | — | CN | disclosed |
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
| US-5266577-A | Method of treating congestive heart failure using carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5198448-A | Cardiovascular disorders | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0531548-A1 | Carbostyril derivatives as anti-thrombotic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |
| US-5053514-A | Side effect reduction; carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | SHH, SMO, DACH1 | NQO1 4871/4885ACACB 4327/4885SIGMAR1 4152/4885 |
| US-20190322673-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | DPYD, PKD1, TYMP | NQO1 36/4885ACACB 3209/4885SIGMAR1 4583/4885 |
| US-11059826-B2 | Pteridinone compounds and uses thereof | DPYD, PKD1, TYMP | NQO1 36/4885ACACB 3209/4885SIGMAR1 4583/4885 |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | NQO1 4173/4885ACACB 3551/4885SIGMAR1 1240/4885 |
| US-20240217995-A1 | COMPOSITIONS FOR CHEMICAL SYNTHESIS OF PEPTIDES | PTMS, DNPEP, ANPEP | NQO1 4729/4885ACACB 2745/4885SIGMAR1 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.