Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 18/20 | 0.63 |
| ▸ | GABRP | O00591 | 1/20 | 0.63 |
| ▸ | GABRD | O14764 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | KLK3 | P07288 | 1/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.63 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.63 |
| ▸ | GABRE | P78334 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788384 | 0.91 | AR (0.63) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL21788383 | 0.90 | AR (0.67) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL10052166 | 0.89 | ABCG2 (0.66) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL15506546 | 0.87 | AR (0.66) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL189993 | 0.87 | ABCG2 (0.85) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL26276099 | 0.86 | ABCG2 (0.75) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL27373046 | 0.85 | ABCG2 (0.59) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL17519964 | 0.83 | AR (0.61) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL17940971 | 0.81 | AR (0.66) | ABCG2ARGABRPGABRDNR1I2 | |
| SCHEMBL19599865 | 0.81 | AR (0.58) | ABCG2ARGABRPGABRDNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825308-B1 | THIOHYDANTOIN COMPOUND, COMPOSITION, AND USE THEREOF AS ANDROGEN RECEPTOR ANTAGONISTS | CHANGSHA ZEDA MEDICAL TECH CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| EP-3825308-A1 | COMPOUND, COMPOSITION, AND USE THEREOF IN PREPARATION OF DRUG | Changsha Zeda Medical Tech. Co., Ltd (CN) | 2021-05-26 | — | — | EP | disclosed |
| US-20210115014-A1 | COMPOUND, COMPOSITION, AND USE THEREOF IN PREPARATION OF DRUG | CHANGSHA ZEDA MEDICAL TECH. CO., LTD (CN) | 2021-04-22 | — | — | US | disclosed |
| WO-2020042622-A1 | COMPOUND, COMPOSITION, AND USE THEREOF IN PREPARATION OF DRUG | 长沙泽达医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115014-A1 | COMPOUND, COMPOSITION, AND USE THEREOF IN PREPARATION OF DRUG | AR, MC2R, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ABCG2 69/4885AR 1/4885GABRP 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.