Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24002213 | 0.90 | MAPT (0.50) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL24002418 | 0.87 | MAPT (0.51) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21789053 | 0.86 | POLB (0.46) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21789056 | 0.86 | POLB (0.46) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21789051 | 0.86 | POLB (0.46) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21789268 | 0.80 | PPARG (0.47) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21789058 | 0.80 | PPARG (0.47) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21789284 | 0.80 | PPARG (0.47) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21777358 | 0.79 | MAPT (0.47) | MAPTTSHRPOLBALDH1A1NPSR1 | |
| SCHEMBL21777359 | 0.79 | MAPT (0.47) | MAPTTSHRPOLBALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047251-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-05 | — | — | WO | disclosed |