Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789058 | 1.00 | PPARG (0.47) | PPARGPPARAPOLBALDH1A1MAPT | |
| SCHEMBL21789268 | 1.00 | PPARG (0.47) | PPARGPPARAPOLBALDH1A1MAPT | |
| SCHEMBL24002213 | 0.89 | MAPT (0.50) | POLBALDH1A1MAPTNPSR1TSHR | |
| SCHEMBL21789050 | 0.87 | TRPM8 (0.46) | POLBALDH1A1MAPTNPSR1TSHR | |
| SCHEMBL21789056 | 0.87 | POLB (0.46) | PPARGPOLBALDH1A1MAPTNPSR1 | |
| SCHEMBL21789051 | 0.87 | POLB (0.46) | PPARGPOLBALDH1A1MAPTNPSR1 | |
| SCHEMBL21789053 | 0.83 | POLB (0.46) | POLBALDH1A1MAPTNPSR1TSHR | |
| SCHEMBL21777440 | 0.83 | PPARG (0.42) | PPARGPPARAPOLBALDH1A1MAPT | |
| SCHEMBL24002418 | 0.81 | MAPT (0.51) | POLBALDH1A1MAPTNPSR1TSHR | |
| SCHEMBL21789048 | 0.80 | MAPT (0.53) | POLBALDH1A1MAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047251-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-05 | — | — | WO | disclosed |