Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789280 | 0.84 | F11 (0.45) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL24002402 | 0.83 | CA12 (0.50) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL21777351 | 0.81 | CA12 (0.49) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL2947571 | 0.76 | CA12 (0.62) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL12546048 | 0.74 | CA12 (0.51) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL1119919 | 0.70 | CA12 (0.55) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL30908315 | 0.70 | CA12 (0.55) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL18822108 | 0.70 | CA12 (0.55) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL7264374 | 0.70 | CA12 (0.55) | CA12CA9MAPK1THRBMAPT | |
| SCHEMBL25911641 | 0.70 | CA12 (0.55) | CA12CA9MAPK1THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047251-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-03-05 | — | — | WO | disclosed |