SCHEMBL21789941

SCHEMBL21789941

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc(OCCCOC)c2n1CCC[C@H]1COc2cc(C#N)cc3nc(NC(=O)c4cc(C)nn4CC)n1c23

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21790028 0.98 STING1 (0.60) STING1
SCHEMBL21789644 0.95 STING1 (0.60) STING1
SCHEMBL21790050 0.95 STING1 (0.58) STING1
SCHEMBL31010505 0.94 STING1 (0.64) STING1
SCHEMBL21790016 0.94 STING1 (0.64) STING1
SCHEMBL21776718 0.94 STING1 (0.64) STING1
SCHEMBL31010504 0.94 STING1 (0.64) STING1
SCHEMBL21790029 0.92 STING1 (0.63) STING1
SCHEMBL21789647 0.92 STING1 (0.64) STING1
SCHEMBL23637127 0.91 STING1 (0.63) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12364702-B2 Highly active sting protein agonist compound ADLAI NORTYE BIOPHARMA CO., LTD. (CN) 2025-07-22 US disclosed
US-20240189320-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND ADLAI NORTYE BIOPHARMA CO., LTD. (CN) 2024-06-13 US disclosed
CN-111655682-B High-activity STING protein agonist compound 杭州阿诺生物医药科技有限公司 2024-05-31 CN disclosed
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed
WO-2020042995-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND 杭州阿诺生物医药科技有限公司 2020-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12364702-B2 Highly active sting protein agonist compound STING1, IRF3, MAVS STING1 1/4885
US-20240189320-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND STING1, IRF3, MAVS STING1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.